Day-to-Day Responsibilities
Designing and optimising the chemical synthesis route for an API, from starting materials to the final molecule, with targets for yield and purity.
Running reactions in the lab and trial batches in a kilo lab or pilot plant to test whether the route works.
Scaling up reactions to plant reactors while watching heat, pressure, mixing and solvent-handling risks.
Testing intermediates and the final API with analytical methods such as HPLC and GC to confirm purity and identify impurities.
Writing and reviewing batch manufacturing records, standard operating procedures and technology transfer reports.
Working with production, quality assurance and regulatory teams to meet GMP requirements and prepare data for drug filings.
Investigating deviations and out-of-specification results, finding root causes and recommending corrective action.


